AMERICAN CONSORTIUM FOR SMALL RUMINANT PARASITE CONTROL INVESTIGATIONS ON THE USE OF PLANT SECONDARY COMPOUNDS OF SERICEA LESPEDEZA FOR THE CONTROL OF SHEEP AND GOAT PARASITES

Thomas Terrill

Abstract


Introduction: Sericea lespedeza (SL; Lespedeza cuneata) is a warm-season perennial legume well-adapted to the warm, moist climate of the southeastern USA. High in condensed tannins and other secondary compounds, SL has potential as an anti-parasitic nutraceutical forage for sheep and goats in this region and throughout the world where it is adapted. Objectives: To summarize the nearly 20 years’ work of the American Consortium for Small Ruminant Parasite Control (ACSRPC) related to the anti-parasitic properties of SL in the diet of small ruminants. Results: In a series of experiments with goats and sheep fed SL in fresh (grazed), dried (hay, leaf meal, pellets) or preserved (ensiled) forms, this forage showed promising anti-parasitic efficacy against GIN, particularly Haemonchus contortus, and coccidia (Eimeria spp.), lowering gastrointestinal nematodes (GIN) fecal egg counts (FEC), coccidial fecal oocyst counts (FOC), and reducing GIN larval development and worm burdens. Implications: These results indicate the potential of SL as a component of integrated, novel (non-chemical) parasite management programs for on-farm application by small ruminant producers. Conclusions: Sericea lespedeza has very good anti-parasitic activity against GIN and coccidial infection in sheep and goats and has excellent potential as a nutraceutical forage for small ruminant producers, either for their own use or for sale as nutraceutical hay or pellets.

Keywords


Sericea lespedeza; Tannins; Gastrointestinal nematodes; Coccidia; Goats; Sheep

Full Text:

PDF

References


Baek, J., Lee, T. K., Song, J. H., Choi, E., Ko, H. J., Lee, S., Choi, S. U., Lee, S., Yoo, S. W., Kim, S. H. and Kim, K. H., 2018. Lignan glycosides and flavonoid glycosides from the aerial portion of Lespedeza cuneata and their biological evaluations. Molecules, 23(8), p. 1920. https://doi.org/10.3390/molecules23081920

Besier, R. B., Kahn, L. P., Sargison, N. D. and Van Wyk, J. A., 2016. The pathophysiology, ecology and epidemiology of Haemonchus contortus infection in small ruminants. Advances in Parasitology, 93, pp. 95-143. https://doi.org/10.1016/bs.apar.2016.02.022

Botha, H., 2015. The use of sericea lespedeza (smart man’s Lucerne) in South Africa. In Proceedings of the WWWW 2015 International Congress Sustainable Parasitic Control, Pretoria, South Africa (pp. 1-2).

Burke, J. M., Kaplan, R. M., Miller, J. E., Terrill, T. H., Getz, W. R., Mobini, S., Valencia, E., Williams, M. J., Williamson, L. H. and Vatta, A. F., 2007. Accuracy of the FAMACHA system for on-farm use by sheep and goat producers in the southeastern United States. Veterinary Parasitology, 147(1-2), pp. 89-95. https://doi.org/10.1016/j.vetpar.2007.03.033

Burke, J. M., Miller, J. E., Mosjidis, J. A. and Terrill, T. H., 2012a. Grazing sericea lespedeza for control of gastrointestinal nematodes in lambs. Veterinary Parasitology, 186(3-4), pp. 507-512. https://doi.org/10.1016/j.vetpar.2011.12.004

Burke, J. M., Miller, J. E., Mosjidis, J. A. and Terrill, T. H., 2012b. Use of a mixed sericea lespedeza and grass pasture system for control of gastrointestinal nematodes in lambs and kids. Veterinary Parasitology, 186(3-4), pp. 328-336. https://doi.org/10.1016/j.vetpar.2011.11.074

Burke, J. M., Miller, J. E., Terrill, T. H., Orlik, S. T., Acharya, M., Garza, J. J. and Mosjidis, J. A., 2013. Sericea lespedeza as an aid in the control of Emeria spp. in lambs. Veterinary parasitology, 193(1-3), pp. 39-46. https://doi.org/10.1016/j.vetpar.2012.11.046

Burke, J. M., Miller, J. E., Terrill, T. H. and Mosjidis, J. A., 2014. The effects of supplemental sericea lespedeza pellets in lambs and kids on growth rate. Livestock Science, 159, pp. 29-36. https://doi.org/10.1016/j.livsci.2013.10.030

Da Silva, N. R. S. and Miller, J. E., 1991. Survey of Eimeria spp. oocysts in feces from Louisiana State University ewes. Veterinary Parasitology, 40(1-2), pp.147-150. https://doi.org/10.1016/0304-4017(91)90091-9

Emery, D. L., Hunt, P. W. and Le Jambre, L. F., 2016. Haemonchus contortus: the then and now, and where to from here? International Journal for Parasitology, 46(12), pp. 755-769. https://doi.org/10.1016/j.ijpara.2016.07.001

Gasser, R. and Samson-Himmelstjerna, G. V., 2016. Haemonchus contortus and haemonchosis–past, present and future trends. Academic Press.

Greif, G., Stephan, B. and Haberkorn, A., 1996. Intraspecific polymorphisms of Eimeria species due to resistance against anticoccidial drugs. Parasitology Research, 82(8), pp. 706-714. https://doi.org/10.1007/s004360050189

Gujja, S., Terrill, T. H., Mosjidis, J. A., Miller, J. E., Mechineni, A., Kommuru, D. S., Shaik, S. A., Lambert, B. D., Cherry, N. M. and Burke, J. M., 2013. Effect of supplemental sericea lespedeza leaf meal pellets on gastrointestinal nematode infection in grazing goats. Veterinary Parasitology, 191(1-2), pp. 51-58. https://doi.org/10.1016/j.vetpar.2012.08.013

Haberkorn, A., 1996. Chemotherapy of human and animal coccidioses: state and perspectives. Parasitology Research, 82(3), pp.193-199. https://doi.org/10.1007/s004360050094

Hamilton, T., Terrill, T., Kommuru, D. S., Rivers, A., Mosjidis, J., Miller, J., Drake, C., Mueller-Harvey, I. and Burke, J., 2017. Effect of supplemental sericea lespedeza pellets on internal parasite infection and nutritional status of grazing goats. Journal of Agricultural Science and Technology A, 7(5), pp. 334-344. https://doi.org/10.17265/2161-6256/2017.05.005

Hoste, H., Torres-Acosta, J. F. J., Sandoval-Castro, C. A., Mueller-Harvey, I., Sotiraki, S., Louvandini, H., Thamsborg, S. M. and Terrill, T. H., 2015. Tannin containing legumes as a model for nutraceuticals against digestive parasites in livestock. Veterinary Parasitology, 212(1-2), pp. 5-17. https://doi.org/10.1016/j.vetpar.2015.06.026

Howell, S. B., Burke, J. M., Miller, J. E., Terrill, T. H., Valencia, E., Williams, M. J., Williamson, L. H., Zajac, A. M. and Kaplan, R. M., 2008. Prevalence of anthelmintic resistance on sheep and goat farms in the southeastern United States. Journal of the American Veterinary Medical Association, 233(12), pp. 1913-1919. https://doi.org/10.2460/javma.233.12.1913

Kang, H., Yoo, M. J., Yi, S. A., Kim, T. W., Ha, J. W., Na, M. W., Park, K. H., Kim, S. H., Han, J. W., Jang, T. S. and Kim, K. H., 2021. Phytochemical constituents identified from the aerial parts of Lespedeza cuneata and their effects on lipid metabolism during adipocyte maturation. Separations, 8(11), p. 203. https://doi.org/10.3390/separations8110203

Kaplan, R. M. 2004. Drug resistance in nematodes of veterinary importance: a status report. Trends in Parasitology. 20(10), pp. 477-481. https://doi.org/10.1016/j.pt.2004.08.001

Kaplan, R. M., Burke, J. M., Terrill, T. H., Miller, J. E., Getz, W. R., Mobini, S., Valencia, E., Williams, M. J., Williamson, L. H., Larsen, M. and Vatta, A. F., 2004. Validation of the FAMACHA© eye color chart for detecting clinical anemia in sheep and goats on farms in the southern United States. Veterinary parasitology, 123(1-2), pp. 105-120. https://doi.org/10.1016/j.vetpar.2004.06.005

Kommuru, D. S., Barker, T., Desai, S., Burke, J. M., Ramsay, A., Mueller-Harvey, I., Miller, J. E., Mosjidis, J. A., Kamisetti, N. and Terrill, T. H., 2014. Use of pelleted sericea lespedeza (Lespedeza cuneata) for natural control of coccidia and gastrointestinal nematodes in weaned goats. Veterinary Parasitology, 204(3-4), pp. 191-198. https://doi.org/10.1016/j.vetpar.2014.04.017

Kommuru, D. S., Whitley, N. C., Miller, J. E., Mosjidis, J. A., Burke, J. M., Gujja, S., Mechineni, A. and Terrill, T. H., 2015. Effect of sericea lespedeza leaf meal pellets on adult female Haemonchus contortus in goats. Veterinary Parasitology, 207(1-2), pp. 170-175. https://doi.org/10.1016/j.vetpar.2014.11.008

Lange, K. C., Olcott, D. D., Miller, J. E., Mosjidis, J. A., Terrill, T. H., Burke, J. M. and Kearney, M. T., 2006. Effect of sericea lespedeza (Lespedeza cuneata) fed as hay, on natural and experimental Haemonchus contortus infections in lambs. Veterinary Parasitology, 141(3-4), pp. 273-278. https://doi.org/10.1016/j.vetpar.2006.06.001

Luginbuhl, J-M., Glennon, H. M., Miller, J. E., and Terrill, T. H., 2013. Grazing and pasture management. Proceedings of the American Consortium for Small Ruminant Parasite Control 10th Anniversary Conference, May 20-22, 2013, Fort Valley, GA, pp. 63-67.

Mechineni, A., Kommuru, D. S., Gujja, S., Mosjidis, J. A., Miller, J. E., Burke, J. M., Ramsay, A., Mueller-Harvey, I., Kannan, G., Lee, J. H. and Kouakou, B., 2014. Effect of fall-grazed sericea lespedeza (Lespedeza cuneata) on gastrointestinal nematode infections of growing goats. Veterinary Parasitology, 204(3-4), pp. 221-228. https://doi.org/10.1016/j.vetpar.2014.06.002

Miller, J. E., Bahirathan, M., Lemarie, S. L., Hembry, F. G., Kearney, M. T. and Barras, S. R., 1998. Epidemiology of gastrointestinal nematode parasitism in Suffolk and Gulf Coast Native sheep with special emphasis on relative susceptibility to Haemonchus contortus infection. Veterinary parasitology, 74(1), pp. 55-74. https://doi.org/10.1016/S0304-4017(97)00094-0

Mortensen, L. L., Williamson, L. H., Terrill, T. H., Kircher, R. A., Larsen, M. and Kaplan, R. M., 2003. Evaluation of prevalence and clinical implications of anthelmintic resistance in gastrointestinal nematodes in goats. Journal of the American Veterinary Medical Association, 223(4), pp. 495-500. https://doi.org/10.2460/javma.2003.223.495

Mosjidis, J. A., and Terrill, T.H., 2013. Sericea lespedeza. Proceedings of the American Consortium for Small Ruminant Parasite Control 10th Anniversary Conference, May 20-22, 2013, Fort Valley, GA, pp. 49-52.

Muir, J. P., Terrill, T. H., Kamisetti, N. R. and Bow, J. R., 2014. Environment, harvest regimen, and ontogeny change Lespedeza cuneata condensed tannin and nitrogen. Crop Science, 54(6), pp. 2903-2909. https://doi.org/10.2135/cropsci2014.02.0143

Muir, J. P., Terrill, T. H., Mosjidis, J. A., Luginbuhl, J. M., Miller, J. E., Burke, J. M. and Coleman, S. W., 2017. Season progression, ontogenesis, and environment affect Lespedeza cuneata herbage condensed tannin, fiber, and crude protein concentrations. Crop Science, 57(1), pp. 515-524. https://doi.org/10.2135/cropsci2016.07.0605

Muir, J. P., Terrill, T. H., Mosjidis, J. A., Luginbuhl, J. M., Miller, J. E., Burke, J. M. and Coleman, S. W., 2018. Harvest regimen changes sericea lespedeza condensed tannin, fiber and protein concentrations. Grassland Science, 64(2), pp. 137-144. https://doi.org/10.1111/grs.12186

Pannell, D., Kouakou, B., Terrill, T. H., Ogunade, I. M., Estrada-Reyes, Z. M., Bryant, V., Taiwo, G., Idowu, M. and Pech-Cervantes, A. A., 2022. Adding dried distillers grains with solubles influences the rumen microbiome of meat goats fed lespedeza or alfalfa-based diets. Small Ruminant Research, 214, p. 106747. https://doi.org/10.1016/j.smallrumres.2022.106747

Papadopoulos, E., Gallidis, E. and Ptochos, S., 2012. Anthelmintic resistance in sheep in Europe: a selected review. Veterinary parasitology, 189(1), pp.85-88. https://doi.org/10.1016/j.vetpar.2012.03.036

Pech-Cervantes, A. A., Terrill, T. H., Ogunade, I. M. and Estrada-Reyes, Z. M., 2021. Meta-analysis of the effects of dietary inclusion of sericea lespedeza (Lespedeza cuneata) forage on performance, digestibility, and rumen fermentation of small ruminants. Livestock Science, 253, p.104707. https://doi.org/10.1016/j.livsci.2021.104707

Salgado, J. A., and Santos, C. D. P., 2016. Overview of anthelmintic resistance of gastrointestinal nematodes of small ruminants in Brazil. Revista Brasileira de Parasitologia Veterinária, 25, pp.3-17. https://doi.org/10.1590/S1984-29612016008

Shaik, S. A., Terrill, T. H., Miller, J. E., Kouakou, B., Kannan, G., Kallu, R. K. and Mosjidis, J. A., 2004. Effects of feeding sericea lespedeza hay to goats infected with Haemonchus contortus. South African Journal of Animal Science, 34(Supplement 1), pp. 248-250.

Shaik, S. A., Terrill, T. H., Miller, J. E., Kouakou, B., Kannan, G., Kaplan, R. M., Burke, J. M. and Mosjidis, J. A., 2006. Sericea lespedeza hay as a natural deworming agent against gastrointestinal nematode infection in goats. Veterinary parasitology, 139(1-3), pp. 150-157. https://doi.org/10.1016/j.vetpar.2006.02.020

Terrill, T. H., Windham, W. R., Hoveland, C. S. and Amos, H. E., 1989. Forage preservation method influences on tannin concentration, intake, and digestibility of sericea lespedeza by sheep. Agronomy Journal, 81(3), pp. 435-439. https://doi.org/10.2134/agronj1989.00021962008100030007x

Terrill, T. H., Windham, W. R., Evans, J. J. and Hoveland, C. S., 1990. Condensed tannin concentraton in sericea lespedeza as influenced by preservation method. Crop Science, 30(1), pp. 219-224. https://doi.org/10.2135/cropsci1990.0011183X003000010047x

Terrill, T. H., Rowan, A. M., Douglas, G. B. and Barry, T. N., 1992. Determination of extractable and bound condensed tannin concentrations in forage plants, protein concentrate meals and cereal grains. Journal of the Science of Food and Agriculture, 58(3), pp.321-329. https://doi.org/10.1002/jsfa.2740580306

Terrill, T. H., Kaplan, R. M., Larsen, M., Samples, O. M., Miller, J. E. and Gelaye, S., 2001. Anthelmintic resistance on goat farms in Georgia: efficacy of anthelmintics against gastrointestinal nematodes in two selected goat herds. Veterinary Parasitology, 97(4), pp. 261-268. https://doi.org/10.1016/S0304-4017(01)00417-4

Terrill, T. H., Larsen, M., Samples, O., Husted, S., Miller, J. E., Kaplan, R. M. and Gelaye, S., 2004. Capability of the nematode-trapping fungus Duddingtonia flagrans to reduce infective larvae of gastrointestinal nematodes in goat feces in the southeastern United States: dose titration and dose time interval studies. Veterinary Parasitology, 120(4), pp. 285-296. https://doi.org/10.1016/j.vetpar.2003.09.024

Terrill, T. H., Mosjidis, J. A., Moore, D. A., Shaik, S. A., Miller, J. E., Burke, J. M., Muir, J. P. and Wolfe, R., 2007. Effect of pelleting on efficacy of sericea lespedeza hay as a natural dewormer in goats. Veterinary Parasitology, 146(1-2), pp. 117-122. https://doi.org/10.1016/j.vetpar.2007.02.005

Terrill, T. H., Miller, J. E., Burke, J. M., Mosjidis, J. A. and Kaplan, R. M., 2012. Experiences with integrated concepts for the control of Haemonchus contortus in sheep and goats in the United States. Veterinary Parasitology, 186(1-2), pp. 28-37. https://doi.org/10.1016/j.vetpar.2011.11.043

Terrill, T. H. and Mosjidis, J. A., 2015, May. Smart man’s lucerne and worm control. In Proceedings of the WWWW 2015 International Congress Sustainable Parasitic Control, Pretoria, South Africa (pp. 25-26).

Van Wyk, J. A. and Bath, G. F., 2002. The FAMACHA system for managing haemonchosis in sheep and goats by clinically identifying individual animals for treatment. Veterinary Research, 33(5), pp. 509-529. https://doi.org/10.1051/vetres:2002036

Waller, P.J. and Chandrawathani, P., 2005. Haemonchus contortus: parasite problem No. 1 from tropics-Polar Circle. Problems and prospects for control based on epidemiology. Tropical Biomedicine, 22(2), pp. 131-137.

Whitley, N., Terrill, T., Griffin, E., Greer-Mapson, L., Singh, A., Owen, V., Dykes, G., Kommuru, D. S., Miller, J., Mosjidis, J. and Punnuri, S., 2018. Effect of ensiling on efficacy of sericea lespedeza against gastrointestinal nematodes and coccidia in goats. Journal of Agricultural Science and Technology A, 8, pp. 377-387. https://doi.org/10.17265/2161-6256/2018.06.005




URN: http://www.revista.ccba.uady.mx/urn:ISSN:1870-0462-tsaes.v27i1.45429

DOI: http://dx.doi.org/10.56369/tsaes.4542



Copyright (c) 2023 Thomas Terrill

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.